Tetra Discovery Partners LLC uses structure-guided drug design to discover mechanistically novel, allosteric inhibitors of phosphodiesterase 4 (PDE4).  Our research focuses on developing new treatments for depression, mild cognitive impairment (MCI) and traumatic brain injury (TBI).

Discovering New Treatments

Tetra Discovery Partners LLC uses structure-guided drug design to discover mechanistically novel, allosteric inhibitors of phosphodiesterase 4 (PDE4).

Based in Grand Rapids, Michigan, our research is dedicated to developing new treatments for patients who suffer from:

Traumatic Brain Injury (TBI)
More than 1.7 million people sustain a TBI, including concussions, in the U.S. each year. Know the warning signs and read about patients who may benefit from our research.

Alzheimer’s disease
Alzheimer’s is a disease that attacks the brain. It is the most common form of dementia. Currently, there is no cure, but more research into drugs and treatments can help. Learn more about cognitive and behavioral symptoms.

Depression
Depression is a common but serious illness with various symptoms. Research indicates depressive illnesses are brain disorders. Chemicals that brain cells use to communicate are out of balance, but it’s been difficult to prove. More research is needed.